Onhealthmeup.com - Kava, also titled kava-kava is a thought that comes from Southeastern Pacific region. It's been used by individual islanders for centuries as a medicinal discourse and also as an effort of their religious ceremonies.
In fact, there are estimates that convey kava has been utilized for a writer than 3,000 geezerhood by Pacific Islanders, and in villages, it's console victimized during gatherings and ethical events. Ocean Islanders may use intoxicant occasionally, or they may do an accomplished inebriant observance if there is a primary reason. In an alcohol function, everyone gathers and shares from a bowlful that's kept in the middle of the locomote. An elite somebody does the serving.
The followers are whatever of the firsthand things to hump roughly intoxicant.
- Kava is also renowned as 'awa and Piper methysticum. It comes from the roots and stems of a runty bush, and it's reasoned non-alcoholic but psychoactive. It's victimized in Fiji, Land, and Hawaii and has been for umpteen geezerhood.
- When kava is equipped traditionally, it's done so by swing the stabilize and turning into a dress and swing them in an element. You can then hook the humor from the bed into a club trough, and it's served as if from a hit concavity.
- Inebriant is said to aid with relaxation, but according to people who use it, it doesn't cloud their thoughts.
- In northwestern society, kava has been increasingly looked as a discourse for anxiousness and stress, as advisable as insomnia. Some research has shown kava may be as powerful as benzodiazepines, tho' investigate is relieve minor on the issue.
- There has been whatsoever distracted most the personality of inebriant on the liver.
- As with another supplement, it's heavy that grouping who track alcohol don't mix it with medicament drugs. This is because it can conquer their effectuality or entity much sedate take personalty.
1) Kava is Anti-Cancer
Kava may Stop Breast Cancer Tumor Growth
Cell-based studies showed that kava decreases breast cancer cell size and increases cell death. Flavokawain A, B, and a flavokawain derivative (FLS) in kava increase the concentration of Bax protein, which activates proteins that cause cell death (cytochrome c and caspase 9). Kava also stops the cell cycle and causes cell death by inhibiting the production of the regulatory proteins PLK1 and FOXM1 [R, R, R].
A cell-based study showed that kava may prevent breast cancer metastasis. Flavokawain A stops the migration and invasion of cancer cells by inhibiting the formation of blood vessels, which cuts off the nutrient supply to tumors. Flavokawain A also decreases the concentration of GLUT 1, a protein that transports glucose to the tumor for energy [R].
Kava may Stop the Progression of Bladder Cancer
Kava stops the progression of bladder cancer and suppresses tumor growth in mice. Flavokawain A activates pathways (caspase-3/9 and Bax protein) that induce tumor cell death and inhibits proteins that prevent cell death (surviving) in mice [R, R].
Kava Inhibits Colon Cancer
In cell-based studies, kava (Flavokawain B) inhibited the growth of colon cancer cells (through the release of cytochrome c and Bax/Bak protein) [R, R].
Kava may Reduce Growth of Prostate Cancer Tumors
Flavokawain B reduces prostate tumor growth, in part by reducing androgen receptors in prostate cells in mice and cell studies. Flavokawain B also kills tumor cells by activating the pathways that cause cell death (caspases and Bax) [R, R].
2) Kava Treats Anxiety
Multiple human studies showed that kava is effective in the treatment of anxiety, regardless of the symptoms and type of disorder (nonspecific anxiety, tension, agitation, agoraphobia, specific phobia, or general anxiety disorder).
Kava activates GABA-A receptors, which produces a calming effect. Kava prevents a decrease in norepinephrine, serotonin, and dopamine levels by inhibiting monoamine oxidase and relaxes muscles by decreasing beta adrenaline receptor activity [R, R, R, R].
3) Kava Helps Treats Sleep Disorders
Kava helps treats sleep disorders like insomnia. Kava reduced stress and severity of insomnia in 24 patients suffering from stress-induced insomnia. 61 patients (in a DB-RCT) suffering from sleep disturbances associated with anxiety, tension, and restlessness were effectively treated with kava extract [R, R].
Kava’s sedative effects are due to the blocking of sodium and calcium ion channels, increased neurotransmitter binding to GABA-A receptors, inhibition of monoamine oxidase B, and an increase of the neurotransmitters noradrenaline and dopamine [R, R].
4) Kava Treats Depression
Kava induced a pleasant mental state while reducing fatigue and anxiety in human and animal studies. It can be used as an alternative to antidepressants (benzodiazepines) in the treatment of depression. Kavalactones in kava increase dopamine, serotonin, GABA (only slightly), and decreases glutamate in cell models [R, R, R].
5) Kava Protects Against Brain Damage Caused by Parkinson’s and Alzheimer’s Disease
Kavalactones extracted from kava prevent brain damage caused by oxidative stress in brain disorders like Parkinson’s and Alzheimer’s disease in mice and cell studies. Kavalactones activate the Nrf2 antioxidant response pathway and increase the concentration of antioxidant enzymes (heme oxygenase-1), which combat oxidative stress [R, R, R].
6) Kava Improves Brain Function
A single dose of kava extract (300 mg) improves accuracy and performance in attention, visual processing, and working memory tasks. Kava pyrones are active in parts of the brain (amygdala, caudate nucleus, and hippocampus) that deal with emotions and brain processes. However, chronic usage and higher doses of kava can result in impaired motor function [R, R].
7) Kava Aids in the Treatment of Drug Addiction
Kava reduces the cravings for addictive drugs in drug-dependent patients in a pilot study. The anti-craving effects of kava are due to dopamine-producing neurons in the reward system of the brain (nucleus accumbens). The kavapyrone desmethoxyyangonin increases dopamine [R, R].
8) Kava Reduces the Severity of Epilepsy and Seizures
Kava helps treat seizures and epilepsy in rats. Alone and in combination with the antiepileptic drug diazepam, kava reduces motor activity, increases the seizure threshold, and enhances the anticonvulsant effect of diazepam.
Kava binds to GABA-A receptors in the brain (hippocampus and frontal cortex) and blocks sodium and calcium ion channels in the brain [R].
9) Kava Relieves Symptoms of Menopause
Perimenopause and menopause symptoms include hot flashes, night sweats, insomnia, and increased anxiety and irritability.
Kava treats anxiety, depression, irritability, and insomnia in 80 perimenopausal women (in a DB-RCT) by activating GABA-A receptors, inhibiting monoamine oxidase-B, and increasing dopamine levels in the brain [R, R, R].
10) Kava may Reduce Inflammation
In cell-based studies, kavain and flavokawains A and B inhibit NF-kB and decrease TNF-alpha, which play a central role in inflammation [R, R].
11) Kava may Boost the Immune System
In mice, flavokawains A and B stimulate white blood cells in the spleen, leading to the secretion of cytokines IL-2 and TNF-alpha as well as increasing the level of immune T cells [R].
Common side effects of kava consumption include headaches, dizziness, drowsiness, fatigue, depression, mild stomach discomfort, and diarrhea. Heavy and frequent use of kava can cause dry eye and dry scaling skin (dermopathy). These side effects are reversible with reduced intake or cessation [R, R, R, R].
Although kava is generally safe to use, using kava supplements containing stems, leaves, and root peelings can cause liver toxicity and damage. It is recommended to use extracts made from peeled kava rhizomes and roots.
Kava is not recommended as the primary agent for anxiety treatment. Avoid using kava in combination with alcohol to prevent liver damage [R, R, R].
Driving and operating heavy machinery is not recommended after consuming kava since kava impairs reaction time and motor skills [R].
Kava can be used recreationally as a psychoactive beverage and has the potential for drug abuse. Drinking kava produces hypnotic, narcotic, and muscle-relaxant effects, which are similar to the effects of alcohol consumption [R].
There have been a few reported cases of kava consumption leading to hepatitis A (a virus transmitted through contaminated water) infection in the liver [R].
Fresh Kava Root Versus Dried Kava Root
Unless you are fortunate enough to live on or visit one of the many tropical islands on which the beautiful kava plant grows, chances are you will only ever come across dried or pre-prepared kava root products. Although in a perfect world, it would be possible to ship fresh kava root to people all over the world, the fresh root does not keep well once it has come out of the ground, making it almost completely impossible to ship safely. On the other hand, dried kava root that is powdered will last for over two years, while dried kava root that has been minimally processed will keep for much longer. Therefore, the preferred method of kava exporters is to sell the dried root rather than trying to deal with all of the complications of shipping the root fresh.
Nevertheless, I want to take a moment to extol the many virtues of fresh kava root, in order to ensure that if any of you ever have the opportunity to work with the fresh root you take it without hesitation. First of all, fresh kava root will almost always be more potent than its dried counterpart, and it will also most likely taste sweeter, as well. It can be difficult to know when buying dried kava root how old it really is - some companies likely leave their dried root sitting on shelves for months, even years - but with fresh kava, you can be assured that it was just harvested. Furthermore, the young lateral roots of kava are known to taste much sweeter than the older taproot of the plant, probably due to different alkaloid contents in the lateral and vertical roots of the plant. When you buy the fresh root, you know exactly what type of kava root you are receiving, as well as what strain it is. This extra level of control will allow you to craft the type of kava experience you really want to have. A final benefit of fresh kava root is that traditional Pacific kava ceremonies always utilize fresh roots, so if you want to experience the real spirit of the kava plant, fresh root is definitely the way to go.
If you do not live in a Kava growing area, and if you cannot foresee a future in which you might have the chance to visit one, don't feel discouraged. I still have good news for you. With a little bit of conscious effort, it is absolutely possible to make your dried kava root experience as close to 'fresh' as possible! The most important thing is to find a supplier that offers high quality dried kava that has not been sitting around for too long. Now, no company is going to admit to selling stale kava, so here are some tips for figuring out which kava supplier is the best:
1. Try to buy your kava direct from a farm, if possible. Kava farms sell to retail outlets and kava bars as well as individuals and therefore tend to have a much higher turnover rate than retailers. Therefore, kava purchased directly from a farm tends to be much fresher. Fortunately, there are plenty of kava farms who will sell directly to you over the internet.
2. The more details a kava seller provides about the kava, the better. Look for mentions of the specific strain that is being used, where the kava is grown, even kavalactone content! There are many types of kava, and this information will help you to discover what types are the most effective for you.
3. Finally, a great way to determine if your batch of dried kava is potent is to notice whether the prepared kava beverage numbs the insides of your mouth and your tongue. The more numbing quality you experience, the more kavalactones are likely to be present in the dried kava.
By using these tips and doing a little research, you will be able to create a dried kava experience that is as close as possible to the fresh kava experience. And if you are ever in a Pacific island region, make a point of searching out some fresh kava root - you won't regret it!